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國家藥品監督管理局組織起草了《化妝品中游離甲醛的檢測方法》《化妝品用化學原料體外兔角膜上皮細胞短時暴露試驗》《皮膚變態反應：局部淋巴結試驗:DA》《皮膚變態反應：局部淋巴結試驗:BrdU-ELISA》《化妝品用化學原料體外皮膚變態反應:直接多肽反應試驗》《化妝品中斑蝥素和氮芥的檢測方法》《化妝品中10種α-羥基酸的檢測方法》《細菌回復突變試驗》《致畸試驗》共9項檢驗方法，經化妝品標準專家委員會全體會議審議通過，現予以發布。其中，前5項檢測方法為新增檢測方法，納入《化妝品安全技術規范（2015年版）》（詳見附件1）；后4項檢測方法為修訂的檢測方法，替換《化妝品安全技術規范（2015年版）》中原有檢測方法（詳見附件1）。
自2020年1月1日起，化妝品注冊、備案及監督檢驗相關檢測應當采用本通告發布的檢測方法。
特此通告。
附件：1.化妝品相關檢驗方法制修訂概況表
2.化妝品中游離甲醛的檢測方法
3.化妝品用化學原料體外兔角膜上皮細胞短時暴露試驗
4.皮膚變態反應：局部淋巴結試驗:DA
5.皮膚變態反應：局部淋巴結試驗:BrdU-ELISA
6.化妝品用化學原料體外皮膚變態反應：直接多肽反應試驗
7.化妝品中斑蝥素和氮芥的檢測方法
8.化妝品中10種α-羥基酸的檢測方法
9.細菌回復突變試驗
10.致畸試驗
國家藥監局
2019年3月13日
附件：
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